Chapter 6 Case-control Study

(In progress)

6.1 Case-control study

• Study design
• Sampling schemes
• Comparisons to other studies
  • randomized experiments
  • retrospective cohort studies
• Motivation for a case-control study
• Estimands in a case-control study

6.2 Logistic regression

• Logistic regression models
• Estimation via maximum likelihood
  • Simple case with analytic solution
  • Score function
  • Fisher information
• Statistical inference
  • Hypothesis testing
  • Confidence intervals
• Diagnostic plots
  • Residuals
  • Pearson residuals

6.3 Generalized linear model

• Basics of generalized linear models
• Practical use of GLM